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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETS1
All Species:
26.97
Human Site:
Y158
Identified Species:
49.44
UniProt:
P14921
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14921
NP_005229.1
441
50408
Y158
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Chimpanzee
Pan troglodytes
XP_001170891
731
79148
S448
E
E
N
S
H
L
T
S
V
P
H
W
I
N
S
Rhesus Macaque
Macaca mulatta
XP_001113198
441
50116
Y158
X
X
X
X
X
S
D
Y
F
I
S
Y
G
I
E
Dog
Lupus familis
XP_546405
441
50378
Y158
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P27577
440
50183
Y158
E
S
C
Y
T
S
D
Y
F
I
S
Y
G
I
E
Rat
Rattus norvegicus
P41156
441
50404
Y158
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508979
473
53725
V190
E
N
S
H
L
T
S
V
P
H
W
I
S
S
N
Chicken
Gallus gallus
P13474
441
50308
Y158
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Frog
Xenopus laevis
P18755
438
50249
Y155
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
S158
M
S
P
M
Q
H
Y
S
P
K
P
T
V
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51022
623
66848
S164
T
T
T
S
S
G
S
S
S
S
G
S
S
S
S
Honey Bee
Apis mellifera
XP_396368
484
53763
D199
P
A
N
Y
S
G
Y
D
E
A
S
E
Y
H
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999698
559
62034
Q213
D
P
A
N
V
P
A
Q
S
S
S
S
S
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
95.9
99
N.A.
97
98.8
N.A.
52.2
95.9
88.6
23.4
N.A.
28.4
32
N.A.
38.1
Protein Similarity:
100
43.2
96.8
99.5
N.A.
98.4
99.3
N.A.
66.5
97.7
93.8
37.6
N.A.
41
42.5
N.A.
50.8
P-Site Identity:
100
6.6
66.6
100
N.A.
93.3
100
N.A.
6.6
100
100
6.6
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
13.3
66.6
100
N.A.
93.3
100
N.A.
26.6
100
100
6.6
N.A.
13.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
54
8
0
0
0
0
0
0
0
% D
% Glu:
62
8
0
0
0
0
0
0
8
0
0
8
0
0
54
% E
% Phe:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
16
0
0
0
0
8
0
54
8
0
% G
% His:
0
0
0
8
8
8
0
0
0
8
8
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
54
0
8
8
54
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
16
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
8
8
0
0
8
0
0
16
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
54
8
16
16
54
16
24
16
16
70
16
24
16
31
% S
% Thr:
8
8
8
0
47
8
8
0
0
0
0
8
0
8
8
% T
% Val:
0
0
0
0
8
0
0
8
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
0
0
0
54
0
0
16
54
0
0
0
54
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _